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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK2
All Species:
10.61
Human Site:
S652
Identified Species:
21.21
UniProt:
Q9H0K1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0K1
NP_056006.1
926
103915
S652
S
C
P
Q
E
E
V
S
Q
Q
Q
E
S
V
S
Chimpanzee
Pan troglodytes
XP_508750
883
99166
S609
S
C
P
Q
E
E
V
S
Q
Q
Q
E
S
V
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546528
993
110460
V726
G
S
C
P
Q
E
E
V
Q
Q
Q
K
T
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFH6
931
104180
S652
S
C
P
Q
E
E
I
S
Q
Q
Q
E
S
V
S
Rat
Rattus norvegicus
Q9R1U5
776
84890
T528
G
L
G
G
G
L
A
T
P
G
L
L
G
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511894
801
88312
S554
S
P
F
L
T
A
R
S
T
A
P
V
L
R
A
Chicken
Gallus gallus
Q9IA88
798
88848
V551
A
S
Q
S
D
A
P
V
L
Q
V
Q
G
C
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
A845
S
A
Y
E
Q
L
T
A
Q
L
L
G
E
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
E1106
H
P
Q
A
Y
G
L
E
E
L
C
Q
F
P
N
Honey Bee
Apis mellifera
XP_397175
718
80391
D471
E
L
F
E
S
S
F
D
S
G
C
P
P
D
Y
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
A887
T
N
S
A
N
M
G
A
S
S
G
G
A
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
E265
V
K
R
I
T
I
P
E
I
R
Q
H
R
W
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
N.A.
84.7
N.A.
90.8
43.2
N.A.
45.2
45.4
N.A.
31.5
N.A.
29.6
37.4
23.8
N.A.
Protein Similarity:
100
95.3
N.A.
87.5
N.A.
94.4
56.7
N.A.
58.6
58.9
N.A.
45.2
N.A.
40
49.3
38.1
N.A.
P-Site Identity:
100
100
N.A.
33.3
N.A.
93.3
6.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
0
0
0
N.A.
P-Site Similarity:
100
100
N.A.
53.3
N.A.
100
13.3
N.A.
20
26.6
N.A.
33.3
N.A.
26.6
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
17
0
17
9
17
0
9
0
0
9
9
17
% A
% Cys:
0
25
9
0
0
0
0
0
0
0
17
0
0
9
0
% C
% Asp:
0
0
0
0
9
0
0
9
0
0
0
0
0
9
0
% D
% Glu:
9
0
0
17
25
34
9
17
9
0
0
25
9
0
0
% E
% Phe:
0
0
17
0
0
0
9
0
0
0
0
0
9
0
9
% F
% Gly:
17
0
9
9
9
9
9
0
0
17
9
17
17
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
9
9
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
17
0
9
0
17
9
0
9
17
17
9
9
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
17
25
9
0
0
17
0
9
0
9
9
9
9
9
% P
% Gln:
0
0
17
25
17
0
0
0
42
42
42
17
0
0
0
% Q
% Arg:
0
0
9
0
0
0
9
0
0
9
0
0
9
9
0
% R
% Ser:
42
17
9
9
9
9
0
34
17
9
0
0
25
9
34
% S
% Thr:
9
0
0
0
17
0
9
9
9
0
0
0
9
9
0
% T
% Val:
9
0
0
0
0
0
17
17
0
0
9
9
0
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _